Question 1

Which of the following factors would be important in determining the concentration of drug that would be reached in the cerebrospinal fluid for treatment of meningitis?

I Oil/water partition coefficient

II Binding to plasma protein

III pKa of the drug

Options :

A : I only

B : III only

C : I and II only

D : II and III only

E : I, II and III

Answer: A

Question 2

Example of drug(s) used in treatment of tuberculosis include:

I- Isoniazid

II- Rifampin

III- Ethambutol

Options :

A : I only

B : III only

C :

I and II only

D : II and III only

E : All are correct

Answer: A

Question 3

Osteoporosis is mainly characterized by:

Options :

A : Loss of joint movements

B : Loss of bone mass

C : Imbalance of uric acid

D : Hormonal imbalance

E : All are correct

Answer: B

Question 4

Enzyme that enables DNA fragments from different sources to be joined:

Options :

A : DNA polymerase

B : DNA gyrase

C : DNA ligase

D : RNA transferase

E : None of the above

Answer: B

Question 5

The pharmacist fills a prescription for sumatriptan 100 mg tablets for a migraine patient. Appropriate information to provide to the patient includes which of the following?

Options :

A : If the sumatriptan does not relieve the headache within four hours, ergotamine may be used.

B :

If no relief is achieved in two hours, sumatriptan may be repeated.

C : If the headache is relieved but another headache occurs eight hours later, sumatriptan may be used for the second headache.

D : The maximum dosage in any 24 hour period is six tablets.

E : If relief is not achieved, no other medication can be used for 24 hours.

Answer: C