Question 1

What is the active ingredient found in the medicine Adalat?

Options :

A : Nifedipine

B : Adalimumab

C : Digoxin

D : Simvastatin

Answer: A

Question 2

Injectable Sulfamethoxazole/Trimethoprim comes as 400mg/80mg/5ml. Physician requests you to dose a

Sulfamethoxazole/Trimethoprim intravenously for PCP. You know the dose is 15mg/kg/day (based on TMP

component) divided q6h.

How many milliliters of Sulfamethoxazole/Trimethoprim of 400mg/80mg/5ml would you need for single

dose? Patient weighs 80kg.

Options :

A : 18.75 mL

B : 75 mL

C : 15 mL

D : 50 mL

E : 16.5 mL

Answer: A

Question 3

Which of the following statements is true regarding Drug-receptor bonds?

Options :

A : Covalent bonds of drugs with receptors are strong and mostly reversible

B : Covalent bonding is much more common than electrostatic bonding in drug-receptor interactions

C : Electrostatic bonds are stronger than covalent bonds

D : Hydrophobic bonds are weak bonds and they are important in the interactions of highly water soluble drugs with the lipids of cell membranes

E : Bond formation of between the acetyl group of aspirin and cyclo-oxygenase enzyme is a covalent bond

Answer: A

Question 4

A physician orders Dopamine 5 mcg/kg/min. The concentration of the Dopamine IV bag is 400 mg in 250 D5W. The patient’s weight is 168 lbs. Calculate the infusion rate in mL/hr.

Options :

A : 10.2mls/hr

B : 5.2mls/hr

C : 14.29mls/hr

D : 22.4mls/hr

E : 0.17mls/hr

Answer: C

Question 5

LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and

NKDA. His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism

and chronic back pain.

Post-op day 1, LN’s medication includes Dexamethasone 8 mg iv q6h with taper dosing, Ondansetron 4 mg

iv q6h prn for N/V, Levothyroxine 0.075 mg po daily, Lisinopril 10 mg po daily, Citalopram 20 mg po daily,

Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10 mg suppository daily prn for constipation,

Famotidine 20 mg iv q12hr, Metoclopramide 10 mg iv q6h, Metformin 500 mg po bid, D51/2NS with 20 K at

125 mls/hour and Hydromorphone PCA at 0.2 mg/hour of basal rate, demand dose 0.1 mg. lock-out every 6

min, one hour limit 2.2 mg/hour. Pertinent morning labs includes serum creatinine 1.4 mg/dl, Mg 1.5 mg/dl,

K 5.0 mmol/L, Na 135 mmol/L.

Which of the following medication may increase LN’s Blood glucose?

Options :

A : Lisinopril

B : Dexamethasone

C : Famotidine

D : Metoclopramide

E : Hydromorphone

Answer: B